Plasma metagenomic next-generation sequencing of microbial cell-free DNA detects pathogens in patients with suspected infected pancreatic necrosis

Plasma metagenomic next-generation sequencing of microbial cell-free DNA detects pathogens in patients with suspected infected pancreatic necrosis

Abstract Background Infected pancreatic necrosis (IPN) is a life-threatening complication of acute pancreatitis (AP). Timely diagnosis of IPN could facilitate appropriate treatment, but there is a lack of reliable non-invasive screening tests. In this study, we aimed to evaluate the diagnostic value...

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Bibliographic Details
Main Authors: Donghuang Hong, Peng Wang, Jingzhu Zhang, Kaiwei Li, Bo Ye, Gang Li, Jing Zhou, Zhihui Tong, Lu Ke, Songjing Shi, Weiqin Li
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Infectious Diseases
Subjects:
Infected pancreatitis necrosis
Acute pancreatitis
Metagenomic next-generation sequencing (mNGS)
Microbial cell-free DNA
Pathogen detection
Online Access:https://doi.org/10.1186/s12879-022-07662-2

Internet

https://doi.org/10.1186/s12879-022-07662-2

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