GSH-activable heterotrimeric nano-prodrug for precise synergistic therapy of TNBC

GSH-activable heterotrimeric nano-prodrug for precise synergistic therapy of TNBC

Combination chemotherapy is an effective approach for triple-negative breast cancer (TNBC) therapy, especially when drugs are administered at specific optimal ratios. However, at present, strategies involving precise and controllable ratios based on effective loading and release of drugs are unavail...

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Bibliographic Details
Main Authors: Xiaojing Zhang, Yansong Chen, Jingwei Tang, Chen Chen, Yanfeng Sun, Hao Zhang, Mengxiang Qiao, Gongsheng Jin, Xianfu Liu
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ratiometric drug loading
Combination therapy
GSH-responsive
Constant drug ratio
Tumor active targeting
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224002592

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http://www.sciencedirect.com/science/article/pii/S0753332224002592

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