The mTORC2 component rictor contributes to cisplatin resistance in human ovarian cancer cells.

The mTORC2 component rictor contributes to cisplatin resistance in human ovarian cancer cells.

Resistance to cisplatin-based therapy is a major cause of treatment failure in human ovarian cancer. A better understanding of the mechanisms of cisplatin resistance will offer new insights for novel therapeutic strategies for this deadly disease. Akt and p53 are determinants of cisplatin sensitivit...

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Bibliographic Details
Main Authors: Akechai Im-aram, Lee Farrand, Seung-Min Bae, Gwonhwa Song, Yong Sang Song, Jae Yong Han, Benjamin K Tsang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086535/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086535/?tool=EBI

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