Endogenous H<sub>2</sub>O<sub>2</sub>-Sensitive and Weak Acidic pH-Triggered Nitrogen-Doped Graphene Nanoparticles (N-GNMs) in the Tumor Microenvironment Serve as Peroxidase-Mimicking Nanozymes for Tumor-Specific Treatment

Endogenous H<sub>2</sub>O<sub>2</sub>-Sensitive and Weak Acidic pH-Triggered Nitrogen-Doped Graphene Nanoparticles (N-GNMs) in the Tumor Microenvironment Serve as Peroxidase-Mimicking Nanozymes for Tumor-Specific Treatment

Nanozymes are emerging as a promising strategy for the treatment of tumors. Herein, to cope with the tumor microenvironment (TME), weak acidity (pH 5.6 to 6.8) and trace amounts of overexpressed hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) (100 µM–1 mM), we report nitrogen-...

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Bibliographic Details
Main Authors: Danyang Liang, Yongzhen Yang, Gongjian Li, Qin Wang, Heting Chen, Xiaoyuan Deng
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Materials
Subjects:
POD-mimicking nanozyme
N-doped graphene
high catalytic activity
pH-triggered
tumor-specific treatment
tumor microenvironment
Online Access:https://www.mdpi.com/1996-1944/14/8/1933

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https://www.mdpi.com/1996-1944/14/8/1933

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