Generation of induced pluripotent stem cells, KCi005-A derived from a female with Parkinsońs disease and homozygous for the PINK1 variant c.1366C > T, p.Gln456*
Disease causing variants in several genes including PINK1 have been identified in hereditary Parkinsońs disease (PD). The mechanism behind this neuronal degeneration is not clarified but it is assumed that mitochondrial dysfunction, e.g. oxidative stress, might be involved. Here we describe the gen...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-02-01
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| Series: | Stem Cell Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506123002659 |