Genetic alteration of human MYH6 is mimicked by SARS-CoV-2 polyprotein: mapping viral variants of cardiac interest

Abstract Acute cardiac injury has been observed in a subset of COVID-19 patients, but the molecular basis for this clinical phenotype is unknown. It has been hypothesized that molecular mimicry may play a role in triggering an autoimmune inflammatory reaction in some individuals after SARS-CoV-2 inf...

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Bibliographic Details
Main Authors: Praveen Anand, Patrick J. Lenehan, Michiel Niesen, Unice Yoo, Dhruti Patwardhan, Marcelo Montorzi, A. J. Venkatakrishnan, Venky Soundararajan
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00914-9