Circulating Microparticles Are Differentially Increased in Lowlanders and Highlanders with High Altitude Induced Pulmonary Hypertension during the Cold Season

Circulating Microparticles Are Differentially Increased in Lowlanders and Highlanders with High Altitude Induced Pulmonary Hypertension during the Cold Season

The role of microparticles (MPs) and cold in high altitude pulmonary hypertension (HAPH) remains unexplored. We investigated the impact of long-term cold exposure on the pulmonary circulation in lowlanders and high-altitude natives and the role of MPs. Pulmonary hemodynamics were evaluated using Dop...

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Bibliographic Details
Main Authors: Akylbek Sydykov, Aleksandar Petrovic, Abdirashit M. Maripov, Marija Gredic, Daniel Gerd Bermes, Nadira Kushubakova, Kubatbek Muratali Uulu, Christina Pilz, Meerim Cholponbaeva, Melis Duishobaev, Samatbek Satybaldyev, Nurgul Satieva, Argen Mamazhakypov, Meerim Sartmyrzaeva, Nazgul Omurzakova, Zhainagul Kerimbekova, Nursultan Baktybek, Cholpon Kulchoroeva, Oleg Pak, Lan Zhao, Norbert Weissmann, Sergey Avdeev, Leonid N. Maslov, Hossein Ardeschir Ghofrani, Ralph Theo Schermuly, Akpay S. Sarybaev, Djuro Kosanovic
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
high altitude
chronic cold exposure
pulmonary hypertension
echocardiography
microparticles
Online Access:https://www.mdpi.com/2073-4409/11/19/2932

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https://www.mdpi.com/2073-4409/11/19/2932

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