TGF-β1 upregulates secreted protein acidic and rich in cysteine expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome

TGF-β1 upregulates secreted protein acidic and rich in cysteine expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome

Abstract Background Ovarian hyperstimulation syndrome (OHSS) is a serious complication during in vitro fertilization (IVF) treatment. The upregulation of ovarian transforming growth factor-beta 1 (TGF-β1) is involved in the development of OHSS. The secreted protein acidic and rich in cysteine (SPARC...

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Bibliographic Details
Main Authors: Xuan Dang, Lanlan Fang, Qiongqiong Jia, Ze Wu, Yanjie Guo, Boqun Liu, Jung-Chien Cheng, Ying-Pu Sun
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cell Communication and Signaling
Subjects:
SPARC
TGF-β1
Granulosa cells
OHSS
Ovary
Online Access:https://doi.org/10.1186/s12964-023-01123-2

Internet

https://doi.org/10.1186/s12964-023-01123-2

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