Interaction of HDAC2 with SARS-CoV-2 NSP5 and IRF3 Is Not Required for NSP5-Mediated Inhibition of Type I Interferon Signaling Pathway

Interaction of HDAC2 with SARS-CoV-2 NSP5 and IRF3 Is Not Required for NSP5-Mediated Inhibition of Type I Interferon Signaling Pathway

ABSTRACT Over the last 2 years, several global virus-host interactome studies have been published with SARS-CoV-2 proteins with the purpose of better understanding how specific viral proteins can subvert or utilize different cellular processes to promote viral infection and pathogenesis. However, mo...

Full description

Bibliographic Details
Main Authors: Nenavath Gopal Naik, See-Chi Lee, Beatriz H. S. Veronese, Zhe Ma, Zsolt Toth
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
HDAC2
NSP5
SARS-CoV-2
type I IFN signaling
interferons
protein-protein interactions
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02322-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02322-22

Similar Items