The Second Highest Prevalence of Celiac Disease Worldwide: Genetic and Metabolic Insights in Southern Brazilian Mennonites

The Second Highest Prevalence of Celiac Disease Worldwide: Genetic and Metabolic Insights in Southern Brazilian Mennonites

Celiac disease (CD), despite its high morbidity, is an often-underdiagnosed autoimmune enteropathy. Using a modified version of the Brazilian questionnaire of the 2013 National Health Survey, we interviewed 604 Mennonites of Frisian/Flemish origin that have been isolated for 25 generations. A subgro...

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Bibliographic Details
Main Authors: Luana Caroline Oliveira, Amanda Coelho Dornelles, Renato Mitsunori Nisihara, Estevan Rafael Dutra Bruginski, Priscila Ianzen dos Santos, Gabriel Adelman Cipolla, Stefanie Epp Boschmann, Iara José de Messias-Reason, Francinete Ramos Campos, Maria Luiza Petzl-Erler, Angelica Beate Winter Boldt
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Genes
Subjects:
celiac disease
Mennonites
HLA-DQ2.5
HLA-DQ8
founder effect
glutathione
Online Access:https://www.mdpi.com/2073-4425/14/5/1026

Internet

https://www.mdpi.com/2073-4425/14/5/1026

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