New Insights Into Mitochondrial DNA Reconstruction and Variant Detection in Ancient Samples

Ancient DNA (aDNA) studies are frequently focused on the analysis of the mitochondrial DNA (mtDNA), which is much more abundant than the nuclear genome, hence can be better retrieved from ancient remains. However, postmortem DNA damage and contamination make the data analysis difficult because of DN...

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Bibliographic Details
Main Authors: Maria Angela Diroma, Alessandra Modi, Martina Lari, Luca Sineo, David Caramelli, Stefania Vai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.619950/full