Loss of Homeostatic Microglia Signature in Prion Diseases

Prion diseases are neurodegenerative diseases that affect humans and animals. They are always fatal and, to date, no treatment exists. The hallmark of prion disease pathophysiology is the misfolding of an endogenous protein, the cellular prion protein (PrP<sup>C</sup>), into its disease-...

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Bibliographic Details
Main Authors: Yue Wang, Kristin Hartmann, Edda Thies, Behnam Mohammadi, Hermann Altmeppen, Diego Sepulveda-Falla, Markus Glatzel, Susanne Krasemann
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/19/2948