Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood

Combined analysis of host IFN-γ, IL-2 and IP-10 as potential LTBI biomarkers in ESAT-6/CFP-10 stimulated blood

Background: Accurate diagnosis of latent tuberculosis infected (LTBI) individuals is important in identifying individuals at risk of developing active tuberculosis. Current diagnosis of LTBI routinely relies on the detection and measurement of immune responses using the Tuberculin Skin Test (TST) an...

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Bibliographic Details
Main Authors: Antony M. Rapulana, Thabo Mpotje, Omolara O. Baiyegunhi, Hlumani Ndlovu, Theresa K. Smit, Timothy D. McHugh, Mohlopheni J. Marakalala
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Molecular Medicine
Subjects:
tuberculosis
latent tuberculosis infection
diagnostic biomarkers
LTBI (latent TB infection)
IP-10 (IFN-γ inducible protein 10)
interferon gamma (IFN-γ)
Online Access:https://www.frontiersin.org/articles/10.3389/fmmed.2024.1345510/full

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https://www.frontiersin.org/articles/10.3389/fmmed.2024.1345510/full

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