Immunisation with Transgenic <i>L. tarentolae</i> Expressing Gamma Glutamyl Cysteine Synthetase from Pathogenic <i>Leishmania</i> Species Protected against <i>L. major</i> and <i>L. donovani</i> Infection in a Murine Model

Leishmaniasis is a protozoan disease responsible for significant morbidity and mortality. There is no recommended vaccine to protect against infection. In this study, transgenic <i>Leishmania tarentolae</i> expressing gamma glutamyl cysteine synthetase (γGCS) from three pathogenic specie...

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Bibliographic Details
Main Authors: Derya Topuz Ata, Muattaz Hussain, Michael Jones, Jonathan Best, Martin Wiese, Katharine Christine Carter
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/11/5/1322