Diagnostic performance of glomerular PLA2R and THSD7A antibodies in biopsy confirmed primary membranous nephropathy in South Africans

Diagnostic performance of glomerular PLA2R and THSD7A antibodies in biopsy confirmed primary membranous nephropathy in South Africans

Abstract Background: Serum and tissue-based tests using phospholipase A2 receptor 1 (PLA2R) and thrombospondin type-1 domain containing 7A (THSD7A) are established immune biomarkers for the diagnosis of primary membranous nephropathy (PMN). This study assessed the diagnostic performance of these bio...

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Bibliographic Details
Main Authors: Bingileki F Lwezaula, Oluwatoyin I Ameh, Udeme E Ekrikpo, Francois CJ Botha, Ugochi S Okpechi-Samuel, Nicola Wearne, Pierre Ronco, Aminu K Bello, Ikechi G. Okpechi
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Nephrology
Subjects:
Africans
Primary membranous nephropathy
Lupus nephritis
PLA2R
THSD7A
Online Access:https://doi.org/10.1186/s12882-020-02216-7

Internet

https://doi.org/10.1186/s12882-020-02216-7

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