Ectopic Spacer Acquisition in <i>Streptococcus thermophilus</i> CRISPR3 Array

<i>Streptococcus thermophilus</i> relies heavily on two type II-A CRISPR-Cas systems, CRISPR1 and CRISPR3, to resist siphophage infections. One hallmark of these systems is the integration of a new spacer at the 5′ end of the CRISPR arrays following phage infection. However, we have prev...

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Bibliographic Details
Main Authors: Rodrigo Achigar, Martina Scarrone, Geneviève M. Rousseau, Cécile Philippe, Felipe Machado, Valentina Duvós, María Pía Campot, Moïra B. Dion, Yuyu Shao, María Julia Pianzzola, Sylvain Moineau
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/9/3/512