Pathophysiology of Slow-Flow Vascular Malformations: Current Understanding and Unanswered Questions

Background:. Slow-flow vascular malformations include venous, lymphatic, and lymphaticovenous malformations. Recent studies have linked genetic variants hyperactivating either the PI3K/AKT/mTOR and/or RAS/RAF/MAPK signaling pathways with slow-flow vascular malformation development, leading to the us...

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Bibliographic Details
Main Authors: Averill Clapp, Carrie J. Shawber, June K. Wu
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2023-09-01
Series:Journal of Vascular Anomalies
Online Access:http://journals.lww.com/10.1097/JOVA.0000000000000069