Biotin controls intestinal stem cell mitosis and host-microbiome interactions

Summary: Diet is a key regulator of metabolism and interacts with the intestinal microbiome. Here, we study the role of the Drosophila intestinal stem cell (ISC)-specific biotin transporter Smvt in midgut homeostasis, infection-induced regeneration, and tumorigenesis. We show that Smvt-transported b...

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Bibliographic Details
Main Authors: Constantina Neophytou, Chrysoula Pitsouli
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722002418