Antithrombotic Effects of Fostamatinib in Combination with Conventional Antiplatelet Drugs

Antithrombotic Effects of Fostamatinib in Combination with Conventional Antiplatelet Drugs

New antithrombotic medications with less effect on haemostasis are needed for the long-term treatment of acute coronary syndromes (ACS). The platelet receptor glycoprotein VI (GPVI) is critical in atherothrombosis, mediating platelet activation at atherosclerotic plaque. The inhibition of spleen tyr...

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Bibliographic Details
Main Authors: Maan H. Harbi, Christopher W. Smith, Fawaz O. Alenazy, Phillip L. R. Nicolson, Alok Tiwari, Steve P. Watson, Mark R. Thomas
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
fostamatinib
R406
Syk
tyrosine kinase
antiplatelet therapy
antithrombotic therapy
Online Access:https://www.mdpi.com/1422-0067/23/13/6982

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https://www.mdpi.com/1422-0067/23/13/6982

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