Differential Role of Rapamycin in Epidermis-Induced IL-15-IGF-1 Secretion via Activation of Akt/mTORC2

Differential Role of Rapamycin in Epidermis-Induced IL-15-IGF-1 Secretion via Activation of Akt/mTORC2

Backgroud/Aims: The effects of rapamycin (RPM) on wound healing have been previously studied. However, reciprocal contradictory data have been reported, and the underlying mechanism remains unclear. This study aims to uncover differential role of RPM in regulation of wound healing and explore the po...

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Main Authors: Yang Bai, Rui Xu, Xueyuan Zhang, Xiaorong Zhang, Xiaohong Hu, Yashu Li, Haisheng Li, Meixi Liu, Zhenggen Huang, Rongshuai Yan, Weifeng He, Gaoxing Luo, Jun Wu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Rapamycin
Akt/mTORC2
IL-15
IGF-1
Wound healing
Online Access:http://www.karger.com/Article/FullText/479443

Internet

http://www.karger.com/Article/FullText/479443

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