Neutrophil Activation in Acute Hemorrhagic Fever With Renal Syndrome Is Mediated by Hantavirus-Infected Microvascular Endothelial Cells

Neutrophil Activation in Acute Hemorrhagic Fever With Renal Syndrome Is Mediated by Hantavirus-Infected Microvascular Endothelial Cells

Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) in humans. Both diseases are considered to be immunologically mediated but the exact pathological mechanisms are still poorly understood. Neutrophils are considered the first line of defens...

Full description

Bibliographic Details
Main Authors: Tomas Strandin, Satu Mäkelä, Jukka Mustonen, Antti Vaheri
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
hantavirus
HFRS
neutrophils
IL-8
endothelial cells
degranulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02098/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02098/full

Similar Items