C53 Interacting with UFM1-Protein Ligase 1 Regulates Microtubule Nucleation in Response to ER Stress

C53 Interacting with UFM1-Protein Ligase 1 Regulates Microtubule Nucleation in Response to ER Stress

ER distribution depends on microtubules, and ER homeostasis disturbance activates the unfolded protein response resulting in ER remodeling. CDK5RAP3 (C53) implicated in various signaling pathways interacts with UFM1-protein ligase 1 (UFL1), which mediates the ufmylation of proteins in response to ER...

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Bibliographic Details
Main Authors: Anastasiya Klebanovych, Stanislav Vinopal, Eduarda Dráberová, Vladimíra Sládková, Tetyana Sulimenko, Vadym Sulimenko, Věra Vosecká, Libor Macůrek, Agustin Legido, Pavel Dráber
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
CDK5RAP3
ER stress
γ-tubulin
microtubule nucleation
UFL1
Online Access:https://www.mdpi.com/2073-4409/11/3/555

Internet

https://www.mdpi.com/2073-4409/11/3/555

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