Superoxide Enhances the Antitumor Combination of AdMnSOD Plus BCNU in Breast Cancer

Superoxide Enhances the Antitumor Combination of AdMnSOD Plus BCNU in Breast Cancer

Overexpression of manganese superoxide dismutase (MnSOD) can sensitize a variety of cancer cell lines to many anticancer drugs. Recent work has shown that cancer cells can be sensitized to cell killing by raising peroxide levels through increased manganese superoxide dismutase (MnSOD) when combined...

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Bibliographic Details
Main Authors: Joseph J. Cullen, Douglas R. Spitz, Jingru Liu, Lei Yu, Christine J. Weydert, Yuping Zhang, Wenqing G. Sun, Larry W. Oberley
Format: Article
Language:English
Published: MDPI AG 2010-02-01
Series:Cancers
Subjects:
MnSOD
BCNU
hydrogen peroxide
superoxide
adenovirus
breast cancer
Online Access:http://www.mdpi.com/2072-6694/2/1/68/

Internet

http://www.mdpi.com/2072-6694/2/1/68/

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