Effects of a selectively bred novelty-seeking phenotype on the motivation to take cocaine in male and female rats

<p>Abstract</p> <p>Background</p> <p>Gender and enhanced novelty reactivity can predispose certain individuals to drug abuse. Previous research in male and female rats selectively bred for high or low locomotor reactivity to novelty found that bred High Responders (bHRs...

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Bibliographic Details
Main Authors: Cummings Jennifer A, Gowl Brooke A, Westenbroek Christel, Clinton Sarah M, Akil Huda, Becker Jill B
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Biology of Sex Differences
Online Access:http://www.bsd-journal.com/content/2/1/3