Architecture of the human NALCN channelosome

Architecture of the human NALCN channelosome

Abstract NALCN regulates the resting membrane potential by mediating the Na+ leak current in neurons, and it functions as a channelosome in complex with FAM155A, UNC79, and UNC80. Dysfunction of the NALCN channelosome causes a broad range of neurological and developmental diseases called NALCN chann...

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Bibliographic Details
Main Authors: Lunni Zhou, Haobin Liu, Qingqing Zhao, Jianping Wu, Zhen Yan
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-022-00392-4

Internet

https://doi.org/10.1038/s41421-022-00392-4

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