Evaluation of inherited germline mutations in cancer susceptibility genes among pancreatic cancer patients: a single-center study

Evaluation of inherited germline mutations in cancer susceptibility genes among pancreatic cancer patients: a single-center study

Abstract Background Germline mutations in cancer susceptibility genes were identified in pancreatic cancer (PanC) patients with a sporadic disease and in those unselected for family cancer history. Methods With the aim to determine the prevalence of germline predisposition genes mutations in PanC, a...

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Bibliographic Details
Main Authors: Francesca Tavano, Domenica Gioffreda, Andrea Fontana, Orazio Palmieri, Annamaria Gentile, Tiziana Latiano, Anna Latiano, Tiziana Pia Latiano, Matteo Scaramuzzi, Evaristo Maiello, Francesca Bazzocchi, Francesco Perri
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Molecular Medicine
Subjects:
Pancreatic cancer
Genetic testing
Next Generation Sequencing
Germline variants
Prevalence
Cancer family history
Online Access:https://doi.org/10.1186/s10020-023-00600-1

Internet

https://doi.org/10.1186/s10020-023-00600-1

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