A reverse vaccinology approach identified novel recombinant tick proteins with protective efficacy against Rhipicephalus microplus infestation

A reverse vaccinology approach identified novel recombinant tick proteins with protective efficacy against Rhipicephalus microplus infestation

The cattle tick, Rhipicephalus microplus, causes significant economic losses to the cattle industry. Tick control is predominately achieved via pesticide applications. However, alternative control methods such as vaccines are needed due to the tick's capacity to quickly develop pesticide resist...

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Bibliographic Details
Main Authors: Luísa N. Domingues, Kylie G. Bendele, Deanna M. Bodine, Lénaïg Halos, Andre A. Cutolo, Martin Liebstein, Justin Widener, Monica Figueiredo, Yovany Moreno, Christian Epe, Alvimar Jose da Costa, Lucas Vinícius Costa Gomes, Felix D. Guerrero
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Ticks and Tick-Borne Diseases
Subjects:
Reverse vaccinology
In vivo vaccine antigen efficacy trial
Recombinant tick protein
In silico anti-tick vaccine antigen discovery
In vitro protein expression
Antigen discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S1877959X24000967

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http://www.sciencedirect.com/science/article/pii/S1877959X24000967

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