Cationic Carbon Nanoparticles Induce Inflammasome-Dependent Pyroptosis in Macrophages via Lysosomal Dysfunction

Cationic Carbon Nanoparticles Induce Inflammasome-Dependent Pyroptosis in Macrophages via Lysosomal Dysfunction

Carbon nanomaterials, including carbon dots (CDs), form a growing family of engineered nanoparticles (NPs) with widespread applications. As the rapid expansion of nanotechnologies raises safety concerns, interaction of NPs with the immune system is receiving a lot of attention. Recent studies have r...

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Bibliographic Details
Main Authors: Yasmin Arezki, Mickaël Rapp, Luc Lebeau, Carole Ronzani, Françoise Pons
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Toxicology
Subjects:
carbon dot
pyroptosis
caspase-1
inflammasome
lysosome
cathepsin B
Online Access:https://www.frontiersin.org/articles/10.3389/ftox.2022.925399/full

Internet

https://www.frontiersin.org/articles/10.3389/ftox.2022.925399/full

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