Endocannabinoid and cannabinoid-like fatty acid amide levels correlate with pain-related symptoms in patients with IBS-D and IBS-C: a pilot study.

AIMS: Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder, associated with alterations of bowel function, abdominal pain and other symptoms related to the GI tract. Recently the endogenous cannabinoid system (ECS) was shown to be involved in the physiological and pathophysi...

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Main Authors: Jakub Fichna, Jodianne T Wood, Malvina Papanastasiou, Subramanian K Vadivel, Piotr Oprocha, Maciej Sałaga, Marta Sobczak, Anna Mokrowiecka, Adam I Cygankiewicz, Piotr K Zakrzewski, Ewa Małecka-Panas, Wanda M Krajewska, Piotr Kościelniak, Alexandros Makriyannis, Martin A Storr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3874007?pdf=render