Single-Cell RNA Sequencing of Hematopoietic Stem and Progenitor Cells Treated with Gemcitabine and Carboplatin

Treatments that include gemcitabine and carboplatin induce dose-limiting myelosuppression. The understanding of how human bone marrow is affected on a transcriptional level leading to the development of myelosuppression is required for the implementation of personalized treatments in the future. In...

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Bibliographic Details
Main Authors: Niclas Björn, Ingrid Jakobsen, Kourosh Lotfi, Henrik Gréen
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/5/549