Panax notoginseng Saponins Stimulates Neurogenesis and Neurological Restoration After Microsphere-Induced Cerebral Embolism in Rats Partially Via mTOR Signaling

Panax notoginseng Saponins Stimulates Neurogenesis and Neurological Restoration After Microsphere-Induced Cerebral Embolism in Rats Partially Via mTOR Signaling

P. Notoginseng Saponins (PNS), the main active component of herbal medicine Panax notoginseng, has been widely used to treat cerebrovascular diseases. It has been acknowledged that PNS exerted protection on nerve injuries induced by ischemic stroke, however, the long-term impacts of PNS on the resto...

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Bibliographic Details
Main Authors: Jiale Gao, Jianxun Liu, Mingjiang Yao, Wei Zhang, Bin Yang, Guangrui Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
Panax notoginseng saponins
cerebral ischemia
neurogenesis
synaptic plasticity
Akt/mTOR/p70S6K pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.889404/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.889404/full

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