Concatenation of molecular docking and molecular simulation of BACE-1, γ-secretase targeted ligands: in pursuit of Alzheimer’s treatment

Concatenation of molecular docking and molecular simulation of BACE-1, γ-secretase targeted ligands: in pursuit of Alzheimer’s treatment

AbstractIntroduction Alzheimer's disease (AD), the most predominant cause of dementia, has evolved tremendously with an escalating frequency, mainly affecting the elderly population. An effective means of delaying, preventing, or treating AD is yet to be achieved. The failure rate of dementia d...

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Bibliographic Details
Main Authors: Nasimudeen R. Jabir, Md. Tabish Rehman, Khadeejah Alsolami, Shazi Shakil, Torki A. Zughaibi, Raed F. Alserihi, Mohd. Shahnawaz Khan, Mohamed F. AlAjmi, Shams Tabrez
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Annals of Medicine
Subjects:
Alzheimer’s disease
drug development
enzyme targets
molecular docking
multi-targeted ligands
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2021.2009124

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https://www.tandfonline.com/doi/10.1080/07853890.2021.2009124

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