Sepsis Disrupts Mitochondrial Function and Diaphragm Morphology

Sepsis Disrupts Mitochondrial Function and Diaphragm Morphology

BackgroundThe diaphragm is the primary muscle of inspiration, and its dysfunction is frequent during sepsis. However, the mechanisms associated with sepsis and diaphragm dysfunction are not well understood. In this study, we evaluated the morphophysiological changes of the mitochondrial diaphragm 5...

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Main Authors: Thamires Siqueira Oliveira, Anderson Teixeira Santos, Cherley Borba Vieira Andrade, Johnatas Dutra Silva, Natália Blanco, Nazareth de Novaes Rocha, Juliana Woyames, Pedro Leme Silva, Patricia Rieken Macedo Rocco, Wagner Seixas da-Silva, Tânia Maria Ortiga-Carvalho, Flavia Fonseca Bloise
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Physiology
Subjects:
diaphragm
sepsis
mitochondria
CLP
oxidative phosphorylation
muscle
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.704044/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.704044/full

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