NFATc1 Regulation of Dexamethasone-Induced <i>TGFB2</i> Expression Is Cell Cycle Dependent in Trabecular Meshwork Cells

Although elevated TGFβ2 levels appear to be a causative factor in glaucoma pathogenesis, little is known about how TGFβ2 expression is regulated in the trabecular meshwork (TM). Here, we investigated if activation of the cytokine regulator NFATc1 controlled transcription of TGFβ2 in human TM cells b...

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Bibliographic Details
Main Authors: Mark S. Filla, Jennifer A. Faralli, Caleigh R. Dunn, Haania Khan, Donna M. Peters
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/3/504