Functional Enterospheres Derived In Vitro from Human Pluripotent Stem Cells

Functional Enterospheres Derived In Vitro from Human Pluripotent Stem Cells

Intestinal organoids derived from human pluripotent stem cells (hPSCs) are valuable in vitro research models that enable simplified access to human gastrointestinal tissues. Here, we report the in vitro generation of enterospheres (hEnS) from hPSC-derived gastrointestinal epithelial precursors. hEnS...

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Bibliographic Details
Main Authors: Rohan R. Nadkarni, Soumeya Abed, Brian J. Cox, Sonam Bhatia, Jennifer T. Lau, Michael G. Surette, Jonathan S. Draper
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Stem Cell Reports
Subjects:
enterospheres
intestinal organoids
intestine
human pluripotent stem cells
in vitro differentiation
Wnt signaling
innate immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111730334X

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http://www.sciencedirect.com/science/article/pii/S221367111730334X

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