αKlotho decreases after reduced weight-bearing from both spaceflight and hindlimb unloading
Abstract Alpha(α)Klotho, a soluble transmembrane protein, facilitates calcium-phosphorus homeostasis through feedback between bone and kidney and is a potential systemic biomarker for bone-kidney health during spaceflight. We determined if: (1) plasma αKlotho was reduced after both spaceflight aboar...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-06-01
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| Series: | npj Microgravity |
| Online Access: | https://doi.org/10.1038/s41526-022-00203-w |