The screening for anticoagulant rodenticide gene VKORC1 polymorphism in the rat Rattus norvegicus, Rattus tanezumi and Rattus losea in Hong Kong

Abstract Anticoagulants are a major component of rodenticides used worldwide, which function by effectively blocking the vitamin K cycle in rodents. The rat Vitamin K epoxide Reductase Complex (VKORC) subunit 1 is the enzyme responsible for recycling vitamin K, and five substitution mutations (Tyr13...

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Bibliographic Details
Main Authors: Elaine Y. Y. Huang, Sean T. S. Law, Wenyan Nong, Ho Yin Yip, Theethawat Uea-Anuwong, Ioannis Magouras, Jerome H. L. Hui
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16550-3