Chronic Exposure to Malaria Is Associated with Inhibitory and Activation Markers on Atypical Memory B Cells and Marginal Zone-Like B Cells

Chronic Exposure to Malaria Is Associated with Inhibitory and Activation Markers on Atypical Memory B Cells and Marginal Zone-Like B Cells

In persistent infections that are accompanied by chronic immune activation, such as human immunodeficiency virus, hepatitis C virus, and malaria, there is an increased frequency of a phenotypically distinct subset of memory B cells lacking the classic memory marker CD27 and showing a reduced capacit...

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Bibliographic Details
Main Authors: Itziar Ubillos, Joseph J. Campo, Pilar Requena, Maria Ome-Kaius, Sarah Hanieh, Honor Rose, Paula Samol, Diana Barrios, Alfons Jiménez, Azucena Bardají, Ivo Mueller, Clara Menéndez, Stephen Rogerson, Gemma Moncunill, Carlota Dobaño
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
chronic infection
malaria
tolerance
B cells
host–malaria interaction
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2017.00966/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2017.00966/full

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