Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease

Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease

Perturbations in neurogenesis in the adult brain have been implicated in impaired learning and memory. In the present study, we investigated which stages of the neurogenic process are affected in the transgenic YAC128 mouse model of Huntington disease (HD). Hippocampal neuronal proliferation was alt...

Full description

Bibliographic Details
Main Authors: Jessica M. Simpson, Joana Gil-Mohapel, Mahmoud A. Pouladi, Mohamed Ghilan, Yuanyun Xie, Michael R. Hayden, Brian R. Christie
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Neurobiology of Disease
Subjects:
Huntington disease
Adult neurogenesis
Cell proliferation
Dentate gyrus
Subventricular zone
YAC128 transgenic mice
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611000313X

Internet

http://www.sciencedirect.com/science/article/pii/S096999611000313X

Similar Items