Coenzyme Q0, a quinone derivative from Antrodia camphorata, inhibits epithelial-mesenchymal transition by activating the Nrf2 signaling pathway in TGF-β-stimulated adult retinal pigment epithelial cells to improve age-related macular degeneration and proliferative vitreoretinopathy
We investigated the anti-EMT and antifibrotic effects of coenzyme Q0 (CoQ0), a quinone derivative from Antrodia camphorata, in TGF-β-stimulated adult retinal pigment epithelial 19 (ARPE-19) cells. Results showed that CoQ0 treatment reversed TGF-β-stimulated morphological changes from an epithelial t...
Main Authors: | Hsin-Ling Yang, Hung-Rong Yen, I-Chen Chang, Chithravel Vadivalagan, Siang-Jyun Chen, Chuan-Chen Lee, Wei-Chen Jane, Jhih-Hsuan Hseu, You-Cheng Hseu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
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Series: | Journal of Functional Foods |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464623005789 |
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