INGAP-Peptide Variants as a Novel Therapy for Type 1 Diabetes: Effect on Human Islet Insulin Secretion and Gene Expression

INGAP-Peptide Variants as a Novel Therapy for Type 1 Diabetes: Effect on Human Islet Insulin Secretion and Gene Expression

Islet transplantation offers a long-term cure for Type 1 Diabetes (T1D), freeing patients from daily insulin injections. Therapeutic peptides have shown potential to increase the insulin output of pancreatic islets, maximizing the impact of grafted cells. The islet neogenesis-associated protein (ING...

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Bibliographic Details
Main Authors: James M. Porter, Léa Guerassimoff, Francisco Rafael Castiello, André Charette, Maryam Tabrizian
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
islet transplantation
peptide therapeutics
insulin secretion
gene expression
Online Access:https://www.mdpi.com/1999-4923/14/9/1833

Internet

https://www.mdpi.com/1999-4923/14/9/1833

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