Waves of actin and microtubule polymerization drive microtubule-based transport and neurite growth before single axon formation
Many developing neurons transition through a multi-polar state with many competing neurites before assuming a unipolar state with one axon and multiple dendrites. Hallmarks of the multi-polar state are large fluctuations in microtubule-based transport into and outgrowth of different neurites, althou...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-02-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/12387 |