Stat1 confers sensitivity to radiation in cervical cancer cells by controlling Parp1 levels: a new perspective for Parp1 inhibition

Stat1 confers sensitivity to radiation in cervical cancer cells by controlling Parp1 levels: a new perspective for Parp1 inhibition

Abstract Cervical cancer (CC) is the fourth most common cause of cancer-related death in women. According to international guidelines, a standard treatment for locally advanced cervical cancer (LACC) consists of exclusive concurrent chemoradiation treatment (CRT). However, chemoradioresistance and s...

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Bibliographic Details
Main Authors: Giuseppina Raspaglio, Marianna Buttarelli, Flavia Filippetti, Alessandra Battaglia, Alexia Buzzonetti, Giovanni Scambia, Daniela Gallo
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04229-y

Internet

https://doi.org/10.1038/s41419-021-04229-y

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