Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma

Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is one of the most common solid tumors worldwide, characterized by clinical aggressiveness, resistance to conventional chemotherapy, and high lethality. Consequently, there is an urgent need to better delineate the molecular pathogenesis of HCC to develop new preventiv...

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Bibliographic Details
Main Authors: Li Che, Panagiotis Paliogiannis, Antonio Cigliano, Maria G. Pilo, Xin Chen, Diego F. Calvisi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
de novo lipogenesis
FASN
tumor metabolism
precision medicine
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01412/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01412/full

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