Longitudinal profiles of plasma gelsolin, cytokines and antibody expression predict COVID-19 severity and hospitalization outcomes

Longitudinal profiles of plasma gelsolin, cytokines and antibody expression predict COVID-19 severity and hospitalization outcomes

BackgroundPrognostic markers for COVID-19 disease outcome are currently lacking. Plasma gelsolin (pGSN) is an actin-binding protein and an innate immune marker involved in disease pathogenesis and viral infections. Here, we demonstrate the utility of pGSN as a prognostic marker for COVID-19 disease...

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Bibliographic Details
Main Authors: Meshach Asare-Werehene, Michaeline McGuinty, Agatha Vranjkovic, Yannick Galipeau, Juthaporn Cowan, Bill Cameron, Curtis L. Cooper, Marc-André Langlois, Angela M. Crawley, Benjamin K. Tsang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Gelsolin
SARS-CoV-2
COVID-19
IL-6
IP-10
IgG
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1011084/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1011084/full

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