Preparation of Hydrochlorothiazide Nanoparticles for Solubility Enhancement

Preparation of Hydrochlorothiazide Nanoparticles for Solubility Enhancement

Nanoparticles can be considered as a useful tool for improving properties of poorly soluble active ingredients. Hydrochlorothiazide (Class IV of the Biopharmaceutical Classification System) was chosen as a model compound. Antisolvent precipitation-solvent evaporation and emulsion solvent evaporation...

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Bibliographic Details
Main Authors: Eliska Vaculikova, Aneta Cernikova, Daniela Placha, Martin Pisarcik, Pavlina Peikertova, Katerina Dedkova, Ferdinand Devinsky, Josef Jampilek
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
hydrochlorothiazide
nanoparticles
dynamic light scattering
infrared spectroscopy
scanning electron microscopy
solubility
Online Access:http://www.mdpi.com/1420-3049/21/8/1005

Internet

http://www.mdpi.com/1420-3049/21/8/1005

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