Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis
Abstract Background Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss. These sequelae are due to parenchymal brain and inner ear damage primarily induced by the excessive inflammatory reaction in response to bacterial brain in...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-019-1549-6 |