Regionally restricted modulation of Sam68 expression and Arhgef9 alternative splicing in the hippocampus of a murine model of multiple sclerosis

Regionally restricted modulation of Sam68 expression and Arhgef9 alternative splicing in the hippocampus of a murine model of multiple sclerosis

Multiple sclerosis (MS) and its preclinical models are characterized by marked changes in neuroplasticity, including excitatory/inhibitory imbalance and synaptic dysfunction that are believed to underlie the progressive cognitive impairment (CI), which represents a significant clinical hallmark of t...

Full description

Bibliographic Details
Main Authors: Annalisa Adinolfi, Gabriele Di Sante, Luca Rivignani Vaccari, Maria Tredicine, Francesco Ria, Davide Bonvissuto, Valentina Corvino, Claudio Sette, Maria Concetta Geloso
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
multiple sclerosis
experimental autoimmune encephalomyelitis
parvalbumin
neuroinflammation
alternative splicing
hippocampus
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1073627/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.1073627/full

Similar Items