PD-1 and beyond to Activate T Cells in Cutaneous Squamous Cell Cancers: The Case for 4-1BB and VISTA Antibodies in Combination Therapy

Non-melanoma skin cancers (NMSC) have a higher incidence than all other cancers combined with cutaneous squamous cell carcinoma (cSCC), capable of metastasis, representing approximately 20% of NMSCs. Given the accessibility of the skin, surgery is frequently employed to treat localized disease, alth...

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Bibliographic Details
Main Authors: Quentin Wright, Jazmina L. Gonzalez Cruz, James W. Wells, Graham R. Leggatt
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/13/3310