Aurora kinase inhibitors: current status and outlook

The Aurora kinase family comprises of cell cycle-regulated serine/threonine kinases important for mitosis. Their activity and protein expression are cell cycle regulated, peaking during mitosis to orchestrate important mitotic processes including centrosome maturation, chromosome alignment, chromos...

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Bibliographic Details
Main Authors: Vassilios eBavetsias, Spiros eLinardopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00278/full